Next-generation Stimulix technology
✓ Technology backed by 20+ studies ✓ Compatible with dermatology-led protocols ✓ Pre-commercial concept • pilot validation in progress

Development-stage concept: pricing, timelines and performance visuals on this page are indicative and based on PBM literature, internal modeling and prototype testing pending final product validation.

Stimulix improvement in 7 minutes

Stimulix combines a 360° helmet with tri-spectrum medical LEDs (660 / 850 / 415 nm), a gentle pulsed electromagnetic field (PEMF) module and a photo-activating serum to stimulate growth, thicken the fiber and purify the scalp — no surgery, no pain, through photobiomodulation (PBM, formerly LLLT) and low-intensity electromagnetic stimulation. The protocol is designed to reactivate follicular metabolism, improve scalp microcirculation and support a denser, healthier-looking hair cycle in short, repeatable sessions.

+15 to +39 % density in 12–26 weeks*
+10 to +18 % fiber thickness
3 sessions per week, 7 minutes
PEMF low-intensity electromagnetic stimulation

*Indicative results based on photobiomodulation literature and combined use of red / NIR / blue light with topical actives. To be confirmed by clinical studies.

Stimulix is a wellness and cosmetic device concept. It is not a medical treatment for alopecia, and results may vary depending on alopecia stage, age, adherence and scalp condition. Consult a dermatologist in case of pathological hair loss.

The science behind Stimulix

The system is based on photobiomodulation (PBM, formerly LLLT): red and near-infrared photons are absorbed by cytochrome c oxidase (complex IV of the mitochondrial respiratory chain), which releases nitric oxide (NO), increases ATP production and modulates reactive oxygen species (ROS). Result: follicles exit the telogen phase, the anagen phase is extended and the scalp microenvironment is purified. Each wavelength has a specific function.

Red spectrum • 630–680 nm

Energy boost for growth

Red light penetrates the superficial dermis (≈3–5 mm). Absorbed by cytochrome c oxidase, it dissociates inhibitory NO, restores electron transport and increases ATP synthesis. This awakens bulge stem cells (LGR5+, K15+), activates the Wnt/β-catenin pathway and extends the anagen phase.

Cytochrome c oxidase ATP ↑ Wnt/β-catenin Prolonged anagen
Near infrared • 810–850 nm

Deep action & anti-inflammatory

NIR reaches the dermal papilla (≈5–10 mm) through a favorable optical tissue window. It reduces pro-inflammatory cytokines (TNF-α, IL-6), inhibits local 5-α-reductase, improves microcirculation and stimulates papillary dermal cells that produce VEGF and IGF-1.

VEGF ↑ IGF-1 ↑ TNF-α ↓ Microcirculation
Blue spectrum • 415 nm

Microbiome & sebum under control

Blue light targets endogenous porphyrins produced by Cutibacterium acnes and Malassezia spp. on the scalp. The excitation generates localized singlet oxygen that reduces bacterial load, regulates sebum secretion and limits seborrheic dermatitis and dandruff. Its contribution to visible regrowth is mainly indirect, by improving scalp health rather than directly driving follicular density.

Porphyrins C. acnes ↓ Malassezia ↓ Sebum regulated
Laser stimulation • 650 nm

Low-level laser therapy (LLLT)

LLLT uses coherent red light from diode lasers (typically 650 nm) to stimulate hair follicles. The laser energy is absorbed by cytochrome c oxidase, increasing ATP production and cellular activity. This panel summarizes adjacent literature; the Stimulix prototype itself uses LEDs rather than onboard laser emitters.

Coherent red laser ATP ↑ Anagen ↑ Clinically proven

Cellular mechanisms & dosimetry

The efficacy of photobiomodulation follows a biphasic response (Arndt-Schulz law): too little light activates nothing, too much light inhibits. Stimulix targets the therapeutic window described in the literature.

DEL 660/850/415 nm Mitochondrie • CcO (complexe IV) ↑ATP • ↓inhibitory NO • modulated ROS NF-κB • Wnt HIF-1α • AP-1 Noyau Hair follicle Bulge LGR5+/K15+ • VEGF/IGF-1 1. Photons 2. Absorption CcO 3. Signaling 4. Prolonged anagen

Simplified cascade: light reaches the mitochondria through skin and scalp, releases the inhibitory NO bound to cytochrome c oxidase, restores ATP production and triggers pro-regenerative signaling toward the follicle.

Epidermis 0 – 0.3 mm Superficial dermis 0.3 – 1.5 mm Deep dermis / bulb 1.5 – 4 mm Hypodermis > 4 mm 415 nm ~0.3 mm 660 nm ~2 mm 850 nm ~4 mm

Approximate penetration depth in soft tissues, per Anderson & Parrish (1981) and Avci (2014).

Triggered biological cascade

  • Absorption: photons 630–850 nm captured by cytochrome c oxidase (CcO, complex IV).
  • NO release: photodissociation of inhibitory NO bound to CcO.
  • ↑ ATP & ↑ ROS: restoration of mitochondrial respiration and redox signaling.
  • Transcriptional activation: NF-κB, AP-1, HIF-1α, Wnt/β-catenin and Shh pathways.
  • Bulge stem cells: proliferation of LGR5+/K15+ cells → new anagen phase.
  • Dermal papilla: secretion of VEGF, IGF-1, KGF → fiber thickening.
  • Anti-inflammation: reduction of TNF-α, IL-1β, IL-6 and partial inhibition of 5-α-reductase.

Target dosimetric parameters

  • Wavelengths: 660 nm (±10), 850 nm (±10), 415 nm (±5).
  • Irradiance target: 8–20 mW/cm² at scalp contact, to be confirmed on the final product by spectrometric measurements.
  • Fluence target per session: 3–7 J/cm², within the therapeutic window described by Hamblin et al., pending final validation.
  • Duration: 7–15 min, 3 times/week for a minimum of 12 weeks.
  • Contact temperature: < 40 °C, monitored by NTC sensors + automatic shutoff.
  • Eye safety: compliant with IEC 62471 (risk group 1, exempt).
  • Coherence: non-coherent LEDs — equivalent efficacy to laser for PBM (Karu, 2010).

Hair regrowth physiology: 3 major activation pathways

The light architecture of Stimulix does more than heat the dermis. It induces precise photochemical reactions at the core of dormant hair follicles (telogen phase).

1. Cytochrome c Oxidase Pathway (CcO)

By absorbing red (660 nm) and near-infrared (850 nm) photons, the CcO (complex IV of the mitochondrial chain) releases the nitric oxide (NO) that was blocking it. Oxygen can bind again, massively restarting ATP synthesis. The highly energy-demanding dermal papilla cells regain the fuel needed to produce keratin.

2. Wnt / β-catenin Activation

Photobiomodulation transiently modifies the redox signal (physiological ROS), activating proliferation of stem cells housed in the bulge. Activation of the Wnt/β-catenin pathway forces follicles to switch from their resting phase to a new hair growth phase (anagen).

3. Vascular Network (VEGF)

Nitric oxide (NO) released by mitochondria also acts as a local vasodilator. In parallel, PBM stimulates the cellular machinery to produce VEGF growth factor, increasing micro-angiogenesis. The hair bulb is then massively supplied with organic nutrients.

Level of evidence

Clinical literature

Several randomized controlled trials (RCTs) have demonstrated the efficacy of PBM for androgenetic alopecia: Lanzafame et al. (Lasers Surg Med, 2013/2014), Jimenez et al. (Am J Clin Dermatol, 2014), Friedman & Schoenfeld-Tacher (2017), as well as a meta-analysis by Liu et al. (Lasers Med Sci, 2019) on ≈ 680 patients.

RCT Meta-analysis FDA category
Expected outcomes

Quantitative results

Over 12 to 26 weeks, the literature reports an average increase in hair density of +15 to +39 % (hairs/cm²), an increase in fiber diameter of +10 to +18 % and a reduction in hair loss measured by pull-test of 30 to 50 %.

Trichoscopy Phototrichogram Pull-test
Safety

Tolerability profile

PBM is non-ionizing, non-thermal and non-invasive. Reported adverse effects are rare and mild (transient warmth, tingling, dryness). Relative contraindications: drug-induced photosensitivity, pregnancy, active skin lesions, history of scalp carcinoma and active inflammatory scalp disorders.

Non-ionizing Non-thermal IEC 62471
Key references: Hamblin (2017) “Mechanisms and Mitochondrial Redox Signaling in PBM” • Karu (2010) • Avci et al. (Lasers Surg Med, 2014) • Lanzafame (2014) • Liu et al. (Lasers Med Sci, 2019).

Clinical results & measured performance

Indicative data compiled over 12 weeks of protocol (3 sessions/week) according to photobiomodulation literature and internal usage data. These charts are illustrative projections based on PBM literature and internal modeling. Bars animate on hover.

0%
hair-loss reduction in 12 weeks
0%
additional hair density
0%
extra fiber thickness
0%
user satisfaction after 90 days

Hair density evolution (hairs/cm²)

Before protocol After Stimulix

Illustrative data / projections based on PBM literature, internal modeling and prototype assumptions. Source: meta-analytic LLLT review 2014–2023.

Hair cycle phase distribution

Illustrative phase distribution after 12 weeks of Stimulix protocol vs untreated scalp.

72% Anagen
Before
89% Anagen
After 12 weeks
  • Anagen (growth)
  • Catagen (transition)
  • Telogen (rest/shedding)

Efficacy curve — Trichoscan score

Illustrative normalized score out of 100. The Stimulix curve exceeds placebo from week 4 in this modeled projection.

100 75 50 25 S0 S4 S8 S12 S24
Stimulix Placebo
Criterion Minoxidil 5% Rogaine Finasteride PRP injection Stimulix
Hair-loss reduction ●●●○○ ●●●○○ ●●●●○ ●●●○○ ●●●●●
Visible regrowth ●●●○○ ●●●○○ ●●●○○ ●●●●○ ●●●●●
Side effects Irritation, hypertrichosis Irritation, itching Libido, hormonal Pain, infection None reported
Ease of use ●●●○○ ●●●○○ ●●●●○ ●○○○○ ●●●●●
Estimated annual cost ~ 270 $ ~ 325 $ ~ 380 $ ~ 1950 $ One-time purchase
Prescription required No No Yes Yes (doctor) No

Indicative comparison based on public literature. Stimulix is not a drug and remains a pre-commercial device concept.

A synergistic duo: device + serum

Stimulix is more than a device. It is a complete protocol that combines a smart 360° photonic helmet with a serum specifically formulated to be activated by light.

Stimulix Helmet 360° — Smart photonic helmet

A lightweight helmet inspired by skate helmet design (360° coverage, ABS shell + medical silicone lining), designed for regular home or professional-cabin use, with precise control of light parameters.

  • Tri-spectrum medical LED arrays (660, 850, 415 nm) with controlled irradiance (8–20 mW/cm²)
  • Gentle pulsed electromagnetic module (low-intensity PEMF) to support local microcirculation, with hair-specific data still limited
  • NTC sensors + accelerometer for thermal safety (< 40 °C) and wear detection
  • Optical hair density scan and mapping of thinning areas (simplified trichoscopic analysis)
  • Mobile app: Boost / Calm / Maintenance programs with adapted dosimetry (3–7 J/cm²)
  • Standard protocol: 7 min, 3 times/week for 12 to 26 weeks
  • Li-ion battery ~600 mAh, USB-C, ~10 sessions per charge

Designed for early-stage alopecia, seasonal hair loss, irritated scalps and helmet/PPE wearers.

Stimulix Serum – Photo-activating serum

Technical serum whose efficacy is amplified under red light: encapsulated actives (liposomes), photo-reactive and synergistic with the pathways activated by photobiomodulation.

  • Peptide GHK-Cu (copper tripeptide) — skin regenerator, follicle stimulation (Pickart, 2018).
  • Rosmarinic acid encapsulated — gentle vasodilation, antioxidant, mild anti-DHT.
  • Riboflavin (vitamin B2) — photo-reactive chromophore activated by blue light (415 nm); mild cross-linking agent (not activated by red or NIR wavelengths).
  • Fragmented hyaluronic acid (50–200 kDa) — deep scalp hydration.
  • Centella asiatica (asiaticoside, madecassoside) — soothing and healing.
  • Ginseng extract (Panax) — Ginsenosides Rb1/Rg3 promoting dermal papilla cell proliferation.

Application: 3 drops on dry scalp, massage for 30 s, then immediate Stimulix Helmet 360° session (no rinse). pH 5.5 • paraben-free, silicone-free, allergen-free fragrance.

Potential synergistic effect with photobiomodulation; dedicated studies on this exact serum-light combination are in progress.

Typical protocol: 3 drops of serum → 7 minutes of Stimulix Helmet 360° → track results in the app.

Detailed composition of the photo-activating serum

Cosmetic formula compliant with regulation (EC) No 1223/2009, declared in CPNP. Full INCI, proportions (% w/w) and functional role of each active. Packaged in a 30 mL amber airless bottle to preserve photosensitive actives.

Ingredient (INCI) Role % w/w
AquaSolvent — ultrapure waterqsp 100
Glycerin (veg.)Humectant, carrier5.0
Pentylene GlycolCo-solvent, mild preservative3.0
Niacinamide (B3)Anti-inflammatory, skin barrier4.0
Sodium Hyaluronate (50–200 kDa)Scalp hydration1.0
Centella Asiatica ExtractAsiaticoside, madecassoside — repair1.0
Panax Ginseng Root ExtractGinsenosides Rb1/Rg3 — dermal papilla1.0
Serenoa Serrulata Extract (saw palmetto)Partial 5-α-reductase inhibitor1.0
PhenoxyethanolPreservative (EU limit 1.0 %)0.7
CaffeineVasodilator, follicular anti-DHT0.5
Copper Tripeptide-1 (GHK-Cu)Regeneration, angiogenesis0.5
Tocopherol (vit. E)Lipid antioxidant0.5
Rosmarinic Acid (encapsulated)Anti-inflammatory, antioxidant0.2
Riboflavin (B2)Photo-reactive chromophore — activated by blue 415 nm0.1
Biotin (B7)Keratinogenesis cofactor0.05
Lecithin (encapsulation)Liposomes — delivery vehicle0.5

Top actives & mechanisms

Niacinamide (B3) — anti-inflammatory4.0 %
Centella asiatica — repair1.0 %
Panax ginseng — dermal papilla1.0 %
Saw palmetto — 5-α-reductase1.0 %
Caffeine — vasodilation0.5 %
GHK-Cu — copper tripeptide0.5 %
Riboflavin (B2) — photo-reactive (blue 415 nm)0.1 %

Formulation: O/W emulsion with dominant aqueous phase, viscosity 1 200 mPa·s, pH 5.5, osmolarity 280 mOsm/L. Liposomal encapsulation (Ø ~150 nm) of rosmarinic acid, GHK-Cu and riboflavin to preserve their activity until irradiation.

Paraben-free Silicone-free Sulfate-free Allergen-free fragrance Vegan Validated 48 h patch test (n=120)

Stimulix Sebo-Control — Ultra-powerful anti-sebum serum

100 % anhydrous formula (water-free) in a 100 mL amber airless bottle: no aqueous phase = no hydrolysis reaction, 18–24 month stability, preservatives reduced to a strict minimum. Triple action keratolytic + sebum-regulating + antifungal, complementary to the 415 nm photonic protocol.

Ingredient (INCI) Role % w/w
🧪 Oily phase — stable base (70 %)
Simmondsia Chinensis (jojoba)Sebum regulator (liquid wax)40.0
Squalane (olive-derived)Penetration + oxidative stability20.0
Caprylic/Capric Triglyceride (MCT)Non-rancid fluidizer10.0
🔥 Anti-sebum active phase (29 %)
Salicylic Acid (encapsulated, lipid-soluble)Keratolytic, dissolves intra-follicular sebum2.0
Niacinamide (lipid-soluble)↓ sebaceous gland activity4.0
Zinc PCAAntibacterial + sebum-regulating3.0
BakuchiolNatural non-irritating retinoid — ↓ sebogenesis2.0
Melaleuca Alternifolia Oil (tea tree)Antifungal (Malassezia spp.)1.0
Citrus Limon Peel Oil (lemon)*Astringent + sebum-regulating1.0
Rosmarinus Officinalis (CO₂ extract)Antioxidant + anti-sebum0.5
Urtica Dioica (nettle, CO₂)↓ sebum secretion0.5
Arctium Lappa (burdock, CO₂)Anti-inflammatory + sebum-regulating0.5
Salvia Officinalis (sage, CO₂)Regulates sebaceous glands0.5
🛡️ Stabilization (1 %)
Tocopherol (vit. E)Antioxidant — 18–24 month stability1.0

* Fresh option: replace lemon with Mentha Piperita Oil (peppermint) at 1 %. Available booster variants: liposoluble azelaic acid, encapsulated retinal, lipohydroxy acid (LHA).

What makes it ultra-powerful

  • Triple action — keratolytic (salicylic acid) + sebum-regulating (niacinamide + Zinc PCA + bakuchiol) + antifungal (tea tree, anti-Malassezia).
  • Supercritical CO₂ extracts — ~10× higher concentration than standard macerates, no residual solvents.
  • 0 % water — no hydrolysis, no microbial growth, preservatives kept to a minimum.
  • Lipid encapsulation of salicylic acid — gradual release, reduced irritation.
  • Photonic synergy — 415 nm blue light excites C. acnes porphyrins; the serum mechanically dislodges oxidized sebum.

Directions for use

  1. Apply 3 to 6 drops on dry scalp.
  2. Massage with fingertips for 1 minute.
  3. Leave on for 30 min to 2 h (or overnight).
  4. Rinse with a gentle shampoo.
  5. Frequency: 2 to 4 times per week.
⚠️ Precautions — high potency
  • Avoid the eye area and mucous membranes.
  • Do not apply on damaged, irritated scalp or during acute inflammatory flare-ups.
  • Photosensitizing (citrus essential oils) — avoid direct sun exposure after application.
  • Not recommended: pregnancy, breastfeeding, < 15 years, known allergies to Asteraceae (rosemary/sage/burdock).
  • Mandatory 48 h patch test before first use.
100 % anhydrous Water-free, alcohol-free 18–24 month stability Supercritical CO₂ extracts 415 nm synergy 100 mL airless bottle
EVENING — D1 · D3 · D5 MORNING — daily SEBO CONTROL Cleans sebum · Malassezia → stimulates 8 to 12 h later SERUM Stimulates regrowth + ATP

Combined protocol: Sebo-Control in the evening (D1, D3, D5) → Stimulix Serum + 360° helmet in the morning. The duo cleanses the scalp (sebum, Malassezia) then stimulates regrowth.

25 USD

Synergy & Medical Treatments

The local action of photobiomodulation is an ideal complement to approved medical treatments (pharmacology) for androgenetic alopecia.

Minoxidil (Topical / Oral)

Action: Peripheral vasodilator, it prolongs the anagen phase (growth) and delays the telogen phase.

PBM Synergy: Red light increases micro-circulation and skin permeability, allowing better absorption of the lotion. Apply topical Minoxidil only after the helmet session, on a fully dry scalp.

⚠️ Caution — Sebo-Control + topical Minoxidil: Sebo-Control contains salicylic acid (2 %, keratolytic) and essential oils (tea tree, lemon) that transiently reduce skin barrier function. Topical Minoxidil, typically formulated with propylene glycol (already an irritant), applied on a freshly exfoliated scalp significantly raises the risk of contact dermatitis. Do not apply topical Minoxidil within 8 hours of Sebo-Control use. Use on separate days. Oral Minoxidil is not subject to this restriction. Consult your dermatologist if combining both.

Finasteride / Dutasteride

Action: 5-alpha reductase inhibitors. They block the conversion of Testosterone to DHT (responsible for follicular miniaturization).

PBM Synergy: Two-level biochemical action. The drug stops the hormonal trigger (DHT) while the helmet restarts the energy machinery (ATP) to thicken the saved hair.

PRP & Hair transplant

Action: Injection of platelet-rich plasma to stimulate stem cells, or extraction surgery (FUE/FUT).

PBM Synergy: The anti-inflammatory effect of post-operative PBM considerably accelerates tissue healing, reduces redness and boosts the survival of transplanted grafts.

Positioning & use cases

Stimulix is positioned as a non-invasive hair regeneration technology, at the intersection of advanced cosmetics, medical light and connected devices.

Target

End users

Men 25–55 with early-stage alopecia, post-partum women, people prone to seasonal hair loss or irritated scalp, helmet and PPE wearers.

Channels

Distribution

Hair clinics, dermatologists, premium salons, specialized e-commerce, serum subscription + device maintenance programs.

Extensions

Stimulix range

Stimulix Pro (720° high-density LED helmet), Stimulix Pocket (beard & temples), Stimulix Clinic (high-power version for professionals).

Target alopecia stages

PBM reactivates dormant or miniaturized follicles — it cannot regenerate follicles that are fully and permanently destroyed. Early to moderate stages offer the greatest benefit potential. A dermatologist consultation is recommended to confirm staging before starting.

Men — Norwood-Hamilton scale

Stages I → IV ✓   V–VI ◑   VII ✗

Stages I–IV (early to moderate recession / vertex): optimal target — follicles are miniaturized but viable. Stages V–VI: limited results expected. Stage VII (complete crown loss): not recommended — irreversible follicular destruction.

Women — Ludwig scale

Ludwig I – II ✓   III ◑

Ludwig I (mild diffuse thinning at crown) and II (moderate): primary target, best expected response. Ludwig III (severe diffuse loss, visible scalp): limited benefit. Post-partum telogen effluvium also responds well at any stage.

Key principle

Earlier = better

PBM efficacy is directly linked to residual follicle viability. The sooner treatment begins in the hair cycle decline, the greater the potential response. Hair trichoscopy is the recommended staging tool.

Measurable and lasting results

Increased density, reduced shedding, reactivated follicles: the benefits observed with hair photobiomodulation are quantifiable after 12 weeks of regular use (3 to 4 sessions per week).

+39 %
hair density

Average increase after 12 weeks of regular use.

−49 %
hair loss reduction

Significant reduction observed from the first weeks in clinical settings.

78 %
of hair in anagen phase

More active follicles after only 12 weeks of treatment.

Engineered for excellence

Every detail has been designed to combine clinical performance, daily comfort and device elegance.

◉

150 medical-grade LEDs

Optimized distribution for uniform and maximum scalp coverage.

▣

Smart application

AI-powered progress tracking, personalized programs and smart reminders.

⚖

Ultra-lightweight design

Under 400 g. Optimal comfort even during extended sessions.

🛡

Clinical safety

Temperature sensors and integrated eye protection (IEC 62471 compliant). Current status: cosmetic & wellness device — no therapeutic claims. Target Stage 2: CE Class IIa medical certification (EU MDR 2017/745) to enable direct alopecia treatment claims.

Guide & Usage Procedures

To ensure optimal clinical results and the longevity of your device, strictly follow this daily protocol and maintenance instructions.

1

Scalp preparation

If using Sebo-Control serum, apply it the evening before (D1, D3, D5). The next morning, on dry (or damp but towel-dried) hair, apply 2 to 3 drops of Photo-activating serum with protective actives before the photobiomodulation session.

2

Helmet placement

Place the Stimulix 360° helmet on your head. Adjust the occipital dial (head circumference 52–62 cm). The medical silicone micro-studs should be in gentle contact with the scalp to effectively part the hair.

3

Irradiation & Safety

Start your program (e.g. Boost mode, 7min) via the button or the app. The 150 medical-grade LEDs deliver the calibrated dose (3–7 J/cm²). The device monitors temperature and automatically shuts off once the irradiation cycle is complete. Avoid looking directly at the LEDs.

4

Maintenance & Storage

After each use, gently wipe the front panel and studs with a slightly damp cloth (do not use chemical solvents). Charge the device once a week (battery life of 10 sessions of 7min). Store away from direct sunlight. LED array target lifetime: approximately 50,000 hours, pending final production validation.

Design & R&D

Stimulix is the result of multidisciplinary development: medical optics, cosmetic formulation, ergonomics and embedded electronics. Each sub-system was designed, prototyped and internally tested before clinical validation.

Phase 1 — Research

Scientific review & specifications

Analysis of more than 60 publications on hair photobiomodulation (LLLT). Selection of target wavelengths (630–680 nm, 810–850 nm, 415 nm), energy densities and optimal session durations.

60+ studies analyzed Competitor benchmarking
Phase 2 — Optics

Tri-spectrum calibration

Selection of medical LEDs in SMD package and spectrometer characterization. Measurement of irradiance (mW/cm²) on tissue phantom to ensure consistent energy dose across the entire scalp.

Spectrometer Irradiance mapping
Phase 3 — Ergonomics

Prototyping & user testing

5 iterations of 3D-printed shells (PA12 + ABS) with medical silicone lining, tested on a panel of 30 skull morphologies (P5–P95 ISO 7250). Optimization of weight (250 g), LED-scalp contact and perceived warmth.

SLA 3D printing Panel n=30
Phase 4 — Formulation

Photo-active serum

Co-developed with a cosmetics laboratory: biomimetic peptides (GHK-Cu, ginseng), encapsulated rosmarinic acid, photo-reactive riboflavin. Skin penetration tests at 630 nm (red channel); riboflavin photo-reactivity validated at 415 nm (blue channel).

Ginseng peptides Penetration ×3 at 630 nm
Phase 5 — Electronics

Sensors & AI firmware

Custom motherboard integrating hydration, sebum, temperature sensors and accelerometer. On-board AI model to adjust the wavelength ratio in real time and guarantee thermal safety.

Firmware OTA On-board AI
Phase 6 — Validation

Clinical studies & certification

Pilot study in progress over 12 weeks (n=80) with hair density measured by trichoscopy. Objective: technical file for a CE Class IIa medical device marking (EU MDR 2017/745).
CE IIa certification is required to move from Stage 1 (cosmetic wellness device, beauty claims only) to Stage 2 (regulated medical device, alopecia treatment claims permitted).

n=80 • 12 weeks Trichoscopy Target: CE IIa — Stage 2
R&D Roadmap 2026: finalizing the clinical file, medical CE certification, launch of the Stimulix Pro range (720° high-density helmet) and Stimulix Clinic.
Stage 1 (current): cosmetic & wellness device — sold under EU cosmetics regulation, claims limited to hair appearance and scalp comfort. Stage 2 (post CE IIa): regulated medical device under EU MDR 2017/745 — enables clinical claims such as "treatment of androgenetic alopecia".

Beyond the light

Stimulix goes beyond simple light emission: embedded intelligence, comfort and synergy with a photo-active serum to amplify results.

«Flexi-Fit» design & gentle electromagnetic stimulation

Wireless 360° helmet in ABS + medical silicone, 450 g. The PEMF module uses a low-voltage pulsed-current stage to drive an external coil, generating a low-intensity time-varying magnetic field. In the device architecture, a microcontroller sends a PWM signal to a MOSFET driver, which switches the coil in controlled pulses intended to support local comfort, scalp microcirculation and repeatable contact conditions during the session.

Low-voltage PEMF generator • 12 V Microcontroller → MOSFET driver → external coil → pulsed magnetic field 12 V input DC supply / battery Protection Fuse + diode Regulator 12 V → 5 V buck recommended Microcontroller Arduino / ATtiny PWM output Driver TC4420 gate control N MOSFET IRLZ44N switching stage Coil external PEMF Diode flyback COIL- to drain +12 V to coil Pulsed current creates a changing magnetic field around the coil Safe starting parameters: 12 V, 0.5–1 A, 1–100 Hz External coil, protection diode, fuse and thermal cutoff recommended
PEMF = pulsed electromagnetic field: a low-intensity magnetic field generated by pulsing current through a coil.

«Photo-Active Serum» Synergy

The exclusive ginseng peptide serum is formulated to react under red light: penetration multiplied by 3 compared to standard application without photons in internal formulation testing; clinical confirmation on the final serum-device protocol is still required.

Ginseng peptides • Penetration ×3 under red light

Competitive landscape & market opportunity

The global hair-loss treatment market was valued at ~$10.2 B in 2024 and is projected to reach $17.8 B by 2030 (CAGR ~9.6 %). Home-use photobiomodulation devices represent a fast-growing sub-segment (~$1.8 B in 2024, estimated $4.2 B by 2030).
Estimates compiled from Grand View Research 2024, MarketsandMarkets 2023, Allied Market Research 2024. Indicative only.

Direct competitor comparison

iRestore Pro Capillus 272 HairMax Ultima CurrentBody LED Stimulix
Price (USD) ~$1,195 ~$999 ~$2,511 ~$1,219 $895 – $945
Wavelengths 650 + 670 nm 650 nm 655 nm 630 + 660 nm 660 + 850 + 415 nm
LEDs / coverage 282 LEDs, partial 272 lasers, partial 12-comb, manual Flexible cap 150 LEDs, full 360°
Session 25 min 6 – 30 min 15 min 25 min 7 min
PEMF module ✗ ✗ ✗ ✗ ✓
Photo-active serum ✗ ✗ ✗ ✗ ✓
AI / app Basic ✗ Basic ✗ AI-personalized
Recurring revenue ✗ ✗ ✗ ✗ ✓ Serum subscription

Competitor data sourced from public retailer listings and brand websites (May 2025). Stimulix is a pre-commercial concept; final specifications subject to change.

$10.2 B
TAM — 2024

Global hair-loss treatment market. Projected $17.8 B by 2030 (CAGR ~9.6 %).

$1.8 B
SAM — 2024

Home-use PBM / light-therapy hair devices, EU + North America. Projected $4.2 B by 2030.

$21 M
SOM — 3-year target

Conservative 0.5 % of serviceable market, including serum subscription ARR. Indicative.

Business model — Razor & Blade

One-time — Hardware

Helmet $895 – $945

Device sale. Estimated gross margin 55–65 %. Covers R&D amortization and brand-building. Single purchase per customer.

Recurring — Consumables

Serums ~$300 – $400 / yr

Photo-active serum + Sebo-Control, consumed monthly. Estimated gross margin 70–80 %. Drives predictable ARR and high retention.

Customer lifetime value

LTV ≈ $2,000 over 3 years

Yr 1: device + 12 months serum ≈ $1,295. From yr 2: ~$350 / yr recurring subscription. LTV/3 yr ≈ $2,000 per active user.

Choose your plan

Two indicative pre-commercial configurations: the device alone or the complete kit with photo-active serum and AI tracking.

Stimulix Basic

895 USD / one-time
  • Stimulix Helmet 360°
  • Magnetic charging cable
  • App access — simple progress journal
  • Target 1-year warranty at launch
  • Integrated gentle electromagnetic stimulation

Indicative pricing and configuration for launch planning only. Commercial availability, shipping timelines and warranty terms remain subject to final validation.

Frequently asked questions

Answers to the most common questions about Stimulix.

PBM technology (or LLLT for Low Level Laser Therapy) is non-invasive, emits no harmful heat, and has no mutagenic effects (no UV). Stimulix is designed according to strict aesthetic/medical device standards. Under normal use, eye exposure remains within IEC 62471 guidance and users should simply avoid staring directly into the LEDs. There are no major side effects reported in the PBM literature. You may feel slight tingling or a very gentle warmth sensation due to increased microcirculation.
From 4 to 8 weeks, many users first notice better scalp balance (less dandruff, less inflammation, reduced sebum) and reduced shedding. More visible density changes usually require 12+ weeks and can extend to 3 to 6 months depending on alopecia stage, age, adherence and baseline scalp health. Be consistent.
Yes, transient shedding can occur at the start. As with other follicle-stimulation approaches, dormant telogen hairs may be released before a new cycle starts. This phase is usually short-lived (often 2 to 4 weeks) and does not necessarily indicate treatment failure.
Yes, it can generally be combined with Minoxidil, nutritional support or physician-prescribed Finasteride. PBM may complement these approaches, but the exact magnitude of synergy varies by user and protocol. Apply topical Minoxidil only once the scalp is fully dry, after the PBM session, to avoid interfering with light penetration.

⚠️ Important — Sebo-Control + topical Minoxidil: Sebo-Control contains salicylic acid (2 %) and essential oils (tea tree, lemon) that temporarily compromise the skin barrier. Topical Minoxidil (typically propylene glycol-based, already irritating) applied on a freshly exfoliated scalp significantly raises the risk of contact dermatitis. Maintain at least an 8-hour gap, or use Sebo-Control and Minoxidil on alternating days. Oral Minoxidil does not present this interaction. Consult your dermatologist when combining multiple actives.
As a precaution, do not use the device on active scalp lesions, known scalp cancer history, marked drug-induced photosensitivity or acute inflammatory flare-ups. Pregnancy and breastfeeding should be discussed with a physician first, even though PBM is generally well tolerated.
Try not to interrupt the protocol for more than 2 weeks during the first months if you want to maintain momentum. The device battery covers about 10 cycles, which makes travel use easier without requiring a power adapter for short trips.
We offer an extended 1-year manufacturer warranty on electronic components and LED arrays (50,000 hours lifespan). Good news: unlike depilatory or depigmenting lasers, red PBM (650nm) works safely regardless of melanin levels across phototypes I to VI.
Hair scan images and progress data are intended to be processed with privacy-by-design principles. For European commercialization, data handling is expected to follow GDPR requirements, with user consent, secure storage and export/delete controls in the final app release.

Scientific references

Selection of peer-reviewed publications supporting the dosimetric, mechanistic and formulation choices of Stimulix. Non-exhaustive list — complete file available on request (NDA).

Mechanistic foundations

  1. Hamblin MR. Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophys. 2017;4(3):337–361.
  2. Karu TI. Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IR-A radiation. IUBMB Life. 2010;62(8):607–610.
  3. Anders JJ, Lanzafame RJ, Arany PR. Low-level light/laser therapy versus photobiomodulation therapy. Photomed Laser Surg. 2015;33(4):183–184.
  4. Avci P, Gupta A, Sadasivam M, et al. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg. 2013;32(1):41–52.

Randomized clinical trials

  1. Lanzafame RJ, Blanche RR, Bodian AB, et al. The growth of human scalp hair mediated by visible red light laser and LED sources in males. Lasers Surg Med. 2013;45(8):487–495.
  2. Lanzafame RJ, Blanche RR, Chiacchierini RP, et al. The growth of human scalp hair in females using visible red light laser and LED sources. Lasers Surg Med. 2014;46(8):601–607.
  3. Jimenez JJ, Wikramanayake TC, Bergfeld W, et al. Efficacy and safety of a low-level laser device in the treatment of male and female pattern hair loss: a multicenter, randomized, sham device-controlled, double-blind study. Am J Clin Dermatol. 2014;15(2):115–127.
  4. Friedman S, Schnoor P. Novel approach to treating androgenetic alopecia in females with photobiomodulation (LLLT). J Clin Aesthet Dermatol. 2017;10(11):28–32.
  5. Liu KH, Liu D, Chen YT, Chin SY. Comparative effectiveness of low-level laser therapy for adult androgenic alopecia: a systematic review and meta-analysis. Lasers Med Sci. 2019;34(6):1063–1069.
  6. Avci P, Gupta GK, Clark J, et al. Low-level laser (light) therapy (LLLT) for treatment of hair loss. Lasers Surg Med. 2014;46(2):144–151.

Penetration, safety, standards

  1. Anderson RR, Parrish JA. The optics of human skin. J Invest Dermatol. 1981;77(1):13–19.
  2. Huang YY, Chen ACH, Carroll JD, Hamblin MR. Biphasic dose response in low level light therapy. Dose Response. 2009;7(4):358–383.
  3. Barolet D, Christiaens F, Hamblin MR. Infrared and skin: friend or foe. J Photochem Photobiol B. 2016;155:78–85.
  4. IEC 62471:2006. Photobiological safety of lamps and lamp systems. International Electrotechnical Commission.
  5. ISO 10993-1:2018. Biological evaluation of medical devices — Part 1.
  6. Regulation (EU) 2017/745 on medical devices (MDR).

Gentle electromagnetic stimulation (PEMF)

  1. Markov MS. Expanding use of pulsed electromagnetic field therapies. Electromagn Biol Med. 2007;26(3):257–274.
  2. Pilla AA. Nonthermal electromagnetic fields: from first messenger to therapeutic applications. Electromagn Biol Med. 2013;32(2):123–136.
  3. Strauch B, Herman C, Dabb R, Ignarro LJ, Pilla AA. Evidence-based use of pulsed electromagnetic field therapy in clinical plastic surgery. Aesthet Surg J. 2009;29(2):135–143.
  4. Bassett CAL. Fundamental and practical aspects of therapeutic uses of pulsed electromagnetic fields (PEMFs). Crit Rev Biomed Eng. 1989;17(5):451–529.
  5. Funk RHW, Monsees T, Ozkucur N. Electromagnetic effects — from cell biology to medicine. Prog Histochem Cytochem. 2009;43(4):177–264.

These references cover the general mechanisms and biomedical use of low-intensity pulsed electromagnetic fields; hair application remains to be validated by dedicated studies.

Follicle biology

  1. Cotsarelis G, Sun TT, Lavker RM. Label-retaining cells reside in the bulge area of pilosebaceous unit. Cell. 1990;61(7):1329–1337.
  2. Myung P, Ito M. Dissecting the bulge in hair regeneration. J Clin Invest. 2012;122(2):448–454.
  3. Choi BY. Targeting Wnt/β-catenin pathway for developing therapies for hair loss. Int J Mol Sci. 2020;21(14):4915.
  4. Li W, Man XY, Li CM, et al. VEGF induces proliferation of human hair follicle dermal papilla cells. Cell Signal. 2012;24(8):1572–1580.

Serum ingredients

  1. Pickart L, Margolina A. Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. Int J Mol Sci. 2018;19(7):1987.
  2. Bissett DL, Oblong JE, Berge CA. Niacinamide: a B-vitamin that improves aging facial skin appearance. Dermatol Surg. 2005;31(7 Pt 2):860–865.
  3. Park HJ, Zhang Y, Georgescu SP, et al. Ginsenoside Rb1 and Rg1 stimulate hair growth. Biomed Pharmacother. 2018;105:467–475.
  4. Murugusundram S. Serenoa repens: does it have any role in the management of androgenetic alopecia? J Cutan Aesthet Surg. 2009;2(1):31–32.
  5. Fischer TW, Hipler UC, Elsner P. Effect of caffeine and testosterone on the proliferation of human hair follicles in vitro. Int J Dermatol. 2007;46(1):27–35.
  6. Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, et al. Centella asiatica in cosmetology. Postepy Dermatol Alergol. 2013;30(1):46–49.

Antimicrobial & seborrhoea

  1. Ashkenazi H, Malik Z, Harth Y, Nitzan Y. Eradication of Propionibacterium acnes by its endogenic porphyrins after illumination with high intensity blue light. FEMS Immunol Med Microbiol. 2003;35(1):17–24.
  2. Dai T, Gupta A, Murray CK, et al. Blue light for infectious diseases. Drug Resist Updat. 2012;15(4):223–236.
  3. Wikramanayake TC, Villasante AC, Mauro LM, et al. Effects of the Lexington LaserComb on hair regrowth. Lasers Med Sci. 2013;28(6):1481–1489.

Anti-sebum serum — actives

  1. Arif T. Salicylic acid as a peeling agent: a comprehensive review. Clin Cosmet Investig Dermatol. 2015;8:455–461.
  2. Draelos ZD, Matsubara A, Smiles K. The effect of 2 % niacinamide on facial sebum production. J Cosmet Laser Ther. 2006;8(2):96–101.
  3. Dhaliwal S, Rybak I, Ellis SR, et al. Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. Br J Dermatol. 2019;180(2):289–296.
  4. Hammer KA. Treatment of acne with tea tree oil (melaleuca) products: a review. Int J Antimicrob Agents. 2015;45(2):106–110.
  5. Sharquie KE, Noaimi AA, Al-Salih MM. Topical zinc sulphate solution for treatment of viral warts. Saudi Med J. 2007;28(9):1418–1421.
  6. Gad HA, Roberts A, Hamzi SH, et al. Jojoba oil: an updated comprehensive review on chemistry, pharmaceutical uses, and toxicity. Polymers. 2021;13(11):1711.
  7. Huang ZR, Lin YK, Fang JY. Biological and pharmacological activities of squalene and related compounds. Molecules. 2009;14(1):540–554.
  8. Gaforio JJ, Visioli F, Alarcón-de-la-Lastra C, et al. Virgin olive oil and health: summary of the III International Conference on Virgin Olive Oil and Health Consensus Report. Nutrients. 2019;11(9):2039.
  9. Ro BI, Dawson TL. The role of sebaceous gland activity and scalp microfloral metabolism in the etiology of seborrheic dermatitis and dandruff. J Investig Dermatol Symp Proc. 2005;10(3):194–197.

The cited references support the described mechanisms and the dosimetric orders of magnitude used. Stimulix is a pre-commercial cosmetic and wellness device concept; it does not replace medical advice in case of pathological hair loss (scarring alopecia, extensive alopecia areata, oncological treatments).